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Study identifier: NCT04504708 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

Dose-Escalation and Dose-Expansion Study of ZX-101A in Patients With Relapsed/Resistant or Refractory Advanced Hematologic Malignancies

Condition: Non-hodgkin Lymphoma · Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma  ·  Sponsor: Hangzhou Zenshine Pharmaceuticals Co., Ltd.

PhasePhase 1/Phase 2
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

ZX-101A-101 is a Phase 1/2a, first-in-human, open-label, multicenter, multiple-ascending dose study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamic, and preliminary antitumor activity of ZX-101A administered orally (PO) once daily (QD) in 28-day cycles in patients with relapsed/resistant or refractory advanced hematologic malignancies \[Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL), indolent NHL, and other NHL subtypes).

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (6)

Banner MD Anderson Cancer CenterGilbert, Arizona, United States
ACRC/Arizona Clinical Research Center, Inc.Tucson, Arizona, United States
Innovative Clinical Research InstituteLong Beach, California, United States
New Jersey Center for Cancer ResearchBrick, New Jersey, United States
University of Toledo Precision Oncology ResearchToledo, Ohio, United States
Seattle Cancer Care AllianceSeattle, Washington, United States

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Source record: clinicaltrials.gov/study/NCT04504708