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Study identifier: NCT04504383 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

Condition: Ulcerative Colitis Chronic Moderate · Ulcerative Colitis Chronic Severe  ·  Sponsor: Protagonist Therapeutics, Inc.

PhasePhase 2
Planned participants169
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of the study is to evaluate the safety, tolerability, and clinical efficacy of PN-943 450 mg twice daily \[BID\] and PN-943 150 mg BID, compared with placebo BID, in subjects with moderate to severe active Ulcerative Colitis (UC).

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (122)

Protagonist Investigational SiteTucson, Arizona, United States
Protagonist Investigational SiteGarden Grove, California, United States
Protagonist Investigational SiteLos Angeles, California, United States
Protagonist Investigational SiteMurrieta, California, United States
Protagonist Investigational SiteSan Francisco, California, United States
Protagonist Investigational SiteColorado Springs, Colorado, United States
Protagonist Investigational SiteKissimmee, Florida, United States
Protagonist Investigational SiteMiami, Florida, United States
Protagonist Investigational SiteMiami, Florida, United States
Protagonist Investigational SiteMiami, Florida, United States
Protagonist Investigational siteOrlando, Florida, United States
Protagonist Investigational SiteSaint Augustine, Florida, United States

+ 110 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04504383