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Study identifier: NCT04502511 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Heterogeneity of Critical Illness: a Cohort Study

Condition: Critically Ill · Organ Failure, Multiple  ·  Sponsor: University Medical Center Groningen

PhaseN/A
Planned participants5000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Rationale: There is large heterogeneity in disease states of critically ill patients at ICU admittance and there is also large heterogeneity in their disease severity during ICU stay. Still, some patients may show remarkable similarities in disease patterns. There is a lack of understanding of causal mechanisms that lead to divergent outcomes in critically ill patients, and at the same time different diseases may share common underlying, yet unidentified, causal pathways that could explain similarities between different diseases. Objective: To explore the association between patient characteristics and the severity of organ failure in critically ill patients admitted to the ICU Study design: Prospective cohort study Study population: Adult critically ill patients in the ICU Intervention (if applicable): not applicable Main study parameters/endpoints: Maximum severity of organ failure observed during ICU stay measured by the maximum SOFA score and quality of life at one year follow-up

This description comes directly from the study's public registry record.

Talk to the study team

Fredrike Zwiers, PhD  ·  +31 503619838  ·  f.zwiers-blokzijl@umcg.nl

Always discuss trial participation with your own doctor first.

Locations (1)

University Medical Center GroningenGroningen, Provincie Groningen, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT04502511