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Study identifier: NCT04502225 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

Condition: Supine Hypertension · Autonomic Failure  ·  Sponsor: Vanderbilt University Medical Center

PhaseNA
Planned participants44
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.

This description comes directly from the study's public registry record.

Talk to the study team

Bonnie K Black, RN  ·  615-343-6862  ·  bonnie.black@vumc.org

Luis E. Okamoto, MD  ·  (615) 936-6119  ·  luis.e.okamoto@vumc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04502225