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Study identifier: NCT04501523 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After NAC in TNBC

Condition: Triple-negative Breast Cancer  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhasePhase 2
Planned participants460
Who can joinFemale, 18 Years to 80 Years
Healthy volunteersNo

About this study

Positive circulating tumor DNA(ctDNA) status is associated with worse prognosis in breast cancer, especially triple-negative breast cancer(TNBC). Our trial aims to improve the outcome of TNBC patients by using ctDNA to identify patients with high relapse risk. ctDNA positive patients will be randomized to receive boost therapy or standard therapy indicated in NCCN guidelines after NAC.

This description comes directly from the study's public registry record.

Talk to the study team

Shunying Li, MD  ·  +86-15915939702  ·  lishunying@foxmail.com

Yudong Li, MD  ·  020-34071156  ·  910870698@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sunyat-sen Memorial HospitalGuandong, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04501523