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Study identifier: NCT04501120 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML

Condition: Relapsed/Refractory Acute Myeloid Leukaemia · Myeloid Malignancy  ·  Sponsor: Ascentage Pharma Group Inc.

PhasePhase 1/Phase 2
Planned participants682
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety, pharmacokinetic profile of Lisaftoclax (APG-2575) single agent and in combination with HHT/AZA in patients with relapsed/refractory AML and related myeloid malignancies.

This description comes directly from the study's public registry record.

Talk to the study team

Jie Jin, M.D.  ·  +86 571-87236896  ·  jiej0503@163.com

Always discuss trial participation with your own doctor first.

Locations (12)

Peking University People's HospitalBeijing, Beijing Municipality, ChinaRecruiting
Chongqing University Cancer HospitalChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guandong, ChinaRecruiting
Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting
Henan Tumor HospitalZhengzhou, Henan, ChinaRecruiting
Union Hospital medical college Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting
Zhongnan Hospital of Hunan universityWuhan, Hubei, ChinaRecruiting
Xiangya Hospital Central South UniversityChangsha, Hunan, ChinaRecruiting
The First affiliated hospital of Soochow UniversitySuzhou, Jiangsu, ChinaRecruiting
Shanghai The Sixth People' s HospitalShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
West China Hospital of Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
the First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04501120