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Study identifier: NCT04499859 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI

Condition: Myocardial Infarction · Statin Adverse Reaction · HMG-CoA Reductase Inhibitor Toxicity  ·  Sponsor: Kiyuk Chang, MD,PhD

PhasePhase 4
Planned participants3548
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

Combination therapy of rosuvastatin 5mg and ezetimibe 10 mg showed similar achievement rate in decreasing LDL cholesterol level by 50% as single use of rosuvastatin 20 mg. This trial aims to prove non-inferiority of concomitant usage of low dose rosuvastatin and ezetimibe among patients with acute myocardial infarction who went through percutaneous coronary intervention at decreasing major adverse cardiac events compared to the efficacy of single use of high dose rosuvastatin.

This description comes directly from the study's public registry record.

Talk to the study team

Kiyuk Chang, MD,PhD  ·  82-10-9175-2076  ·  kiyuk@catholic.ac.kr

Eun Ho Choo, MD  ·  82-10-8500-4569  ·  cmcchu@catholic.ac.kr

Always discuss trial participation with your own doctor first.

Locations (7)

Bucheon St.Mary HospitalBucheon-si, Gyeonggido, South KoreaRecruiting
St.Vincent's HospitalSuwon, Gyeonggido, South KoreaRecruiting
Uijeongbu St.Mary's HospitalUijeongbu-si, Gyeonggido, South KoreaRecruiting
Daejeon St.Mary's HospitalDaejeon, South KoreaRecruiting
Incheon St.Mary's HospitalIncheon, South KoreaRecruiting
Seoul St.Mary's HospitalSeoul, South KoreaRecruiting
Yeouido St.Mary HospitalSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT04499859