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Study identifier: NCT04498767 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)

Condition: Gynecologic Cancer · Skin Cancer · Head and Neck Cancer  ·  Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized open-label multicentre Phase III superiority study of the effect of adding SBRT to the standard of care treatment on overall survival in patients with rare oligometastatic cancers. Patients will be randomized in a 1:1 ratio between current standard of care treatment vs. standard of care treatment + SBRT to all sites of known metastatic disease. The primary objective of this trial is to assess if the addition of stereotactic body radiotherapy (SBRT) to standard of care treatment improves overall survival (OS) as compared to standard of care treatment alone in patients with rare oligometastatic cancers.

This description comes directly from the study's public registry record.

Talk to the study team

EORTC HQ  ·  +32 2 7744 1611  ·  eortc@eortc.org

Always discuss trial participation with your own doctor first.

Locations (13)

Institut Jules BordetAnderlecht, BelgiumRecruiting
Universitair Ziekenhuis GentGhent, BelgiumRecruiting
Gasthuiszusters Antwerpen - Sint-AugustinusWilrijk, BelgiumRecruiting
Centre Oscar LambretLille, FranceRecruiting
Gustave RoussyVillejuif, FranceRecruiting
Universitaets Krankenhaus Eppendorf - Universitaetsklinikum Hamburg-Eppendorf KE - University Cancer CenterHamburg, Martinistrasse 52, GermanyRecruiting
Istituto Europeo di OncologiaMilan, ItalyRecruiting
Medical University Of GdanskGdansk, Mariana Smoluchowskiego 17, PolandRecruiting
Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska-Curie National Research Institute of OncologyWarsaw, PolandRecruiting
InselspitalBern, SwitzerlandRecruiting
UniversitaetsSpital ZurichZurich, SwitzerlandRecruiting
University Hospitals Birmingham NHS Foundation Trust (UHB) - UHB-Queen Elisabeth Medical CentreBirmingham, United KingdomRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04498767