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Study identifier: NCT04494724 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clazakizumab vs. Placebo - COVID-19 Infection

Condition: COVID-19 Infection  ·  Sponsor: The Methodist Hospital Research Institute

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance). We are proposing to try this drug to treat coronavirus disease 2019 (COVID-19) infection. Patients with COVID-19 infection have been shown to have increases in certain inflammatory processes. Clazakizumab is an antibody (immune system protein) that blocks certain inflammatory processes. The treatment plan is to attempt to inhibit or block these inflammatory processes in order to try to limit the damage COVID-19 causes to the lungs.

This description comes directly from the study's public registry record.

Talk to the study team

Isioma Agboli, MD  ·  713-441-6311  ·  iagboli@houstonmethodist.org

Darrel Cleere, BSN  ·  713-441-6232  ·  dwcleere@houstonmethodist.org

Always discuss trial participation with your own doctor first.

Locations (1)

Houston Methodist HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04494724