Condition: Septic Shock · Sponsor: Centre Hospitalier Intercommunal Creteil
The best strategy for managing fever in patients with septic shock remains unknown. In a pilot study, the investigators showed that fever control at normothermia allowed a better control of shock and evolution of organ failures. In this second trial the investigators will conduct a multicentre, open-label, randomized controlled, superiority trial in which two strategies will be compared: 1. Respect of fever 2. Fever control at normothermia using external cooling The primary end point will be d-60 mortality.
This description comes directly from the study's public registry record.
Frédérique SCHORTGEN, MD · 01 57 02 34 11 · Frederique.schortgen@chicreteil.fr
Camille JUNG, MD · 01 57 02 22 68 · camille.jung@chicreteil.fr
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| CHU Amiens | Amiens, France | Recruiting |
| CHU Angers | Angers, France | Recruiting |
| CH Victor Dupouy | Argenteuil, France | Recruiting |
| Hôpital Nord Franche Comté | Belfort, France | Recruiting |
| CH Cholet | Cholet, France | Recruiting |
| Centre hospitalier intercommunal de Créteil | Créteil, France | Recruiting |
| Hôpital Henri Mondor | Créteil, France | Active Not Recruiting |
| CHD Dijon | Dijon, France | Recruiting |
| CHU Grenoble | Grenoble, France | Recruiting |
| GH Est Francilien | Jossigny, France | Recruiting |
| CHD Vendée | La Roche-sur-Yon, France | Recruiting |
| CHU Kremlin Bicetre | Le Kremlin-Bicêtre, France | Active Not Recruiting |
+ 21 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04494074