Condition: Breast Cancer · Neoadjuvant Therapy · Lymph Node Metastases · Sponsor: Maastricht University Medical Center
Today, the majority of clinically node positive (cN+) breast cancer patients is treated with neoadjuvant systemic therapy (NST). Axillary staging and treatment after NST in cN+ patients are areas of controversy. Patients with a pathological complete response (pCR) of the axillary lymph nodes are not expected to benefit from axillary lymph node dissection (ALND). Hence, less invasive axillary staging procedures are being introduced to avoid unnecessary ALND. However, evidence supporting the safety of replacing ALND by less invasive techniques in terms of oncologic safety and impact on quality of life (QoL) is lacking.
This description comes directly from the study's public registry record.
Sabine de Wild, MD · +31433881574 · s.dewild@maastrichtuniversity.nl
Janine Simons, MD, PhD · j.simons@maastrichtuniversity.nl
Always discuss trial participation with your own doctor first.
| Jeroen Bosch Hospital | 's-Hertogenbosch, Netherlands | Recruiting |
| Northwest Clinics | Alkmaar, Netherlands | Recruiting |
| The Netherlands Cancer Institute | Amsterdam, Netherlands | Recruiting |
| Gelre Hospital | Apeldoorn, Netherlands | Recruiting |
| Rijnstate Hospital | Arnhem, Netherlands | Recruiting |
| Red Cross Hospital | Beverwijk, Netherlands | Recruiting |
| Alexander Monro Hospital | Bilthoven, Netherlands | Recruiting |
| Amphia Hospital | Breda, Netherlands | Recruiting |
| Van Weel-Bethesda | Dirksland, Netherlands | Recruiting |
| Slingeland Hospital | Doetinchem, Netherlands | Recruiting |
| Albert Schweitzer Hospital | Dordrecht, Netherlands | Recruiting |
| Gelderse Vallei Hospital | Ede, Netherlands | Recruiting |
+ 23 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04486495