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Study identifier: NCT04486352 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

Condition: Endometrial Cancer  ·  Sponsor: Alliance Foundation Trials, LLC.

PhasePhase 1/Phase 2
Planned participants148
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study participants into biomarker-matched study cohorts consisting of testing targeted agents.

This description comes directly from the study's public registry record.

Talk to the study team

Quality Management and Compliance  ·  617-732-8727  ·  ClinicalTrials.Queries@alliancefoundationtrials.org

Always discuss trial participation with your own doctor first.

Locations (21)

City of Hope Comprehensive Cancer CenterDuarte, California, United StatesActive Not Recruiting
UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, California, United StatesActive Not Recruiting
Medstar Georgetown Cancer InstituteWashington D.C., District of Columbia, United StatesActive Not Recruiting
Mount Sinai Comprehensive Cancer CenterMiami Beach, Florida, United StatesActive Not Recruiting
University of ChicagoChicago, Illinois, United StatesActive Not Recruiting
University of Kansas Cancer CenterWestwood, Kansas, United StatesActive Not Recruiting
Maine Medical CenterScarborough, Maine, United StatesActive Not Recruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesActive Not Recruiting
University of MinnesotaMinneapolis, Minnesota, United StatesActive Not Recruiting
Washington University School of Medicine Siteman Cancer CenterSt Louis, Missouri, United StatesWithdrawn
Nebraska Methodist HospitalOmaha, Nebraska, United StatesActive Not Recruiting
Englewood HealthEnglewood, New Jersey, United StatesActive Not Recruiting

+ 9 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04486352