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Study identifier: NCT04483206 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Personalized Autologous Transplant for Multiple Myeloma

Condition: Multiple Myeloma  ·  Sponsor: Emory University

PhasePhase 1
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial studies the best dose and side effects of mephalan in treating patients with multiple myeloma who are undergoing stem cell transplant. Chemotherapy drugs, such as mephalan, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial uses a new method of dosing that is based on analysis of each individual's blood levels of melphalan after receiving a part of the dose, termed pharmacokinetic analysis. This may help to learn more about how to dose melphalan correctly and which patients are likely to benefit from a personalized dose.

This description comes directly from the study's public registry record.

Talk to the study team

Craig Hofmeister, MD, MPH  ·  404-778-1900  ·  craig.hofmeister@emory.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Winship Cancer Institute of Emory UniversityAtlanta, Georgia, United StatesRecruiting
University Illinois ChicagoChicago, Illinois, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04483206