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Study identifier: NCT04483076 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Oxaliplatin Combined With S-1(SOX) Neoadjuvant Chemotherapy for Different Cycles in Patients With Gastric Cancer

Condition: Gastric Cancer · Chemotherapy Effect  ·  Sponsor: Chinese PLA General Hospital

PhasePhase 3
Planned participants524
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

RESONANCE-II trial is a prospective, multicenter, randomized, controlled phase III study which will enroll 524 patients in total. Patients with eligibility will be registered, pre-enrolled and receive three cycles of SOX. Then, tumor response evaluation will be carried out. Those who achieve stable disease or progressive disease will be excluded. Patients achieving complete response or partial response will be enrolled and assigned into either group A for another three cycles of SOX (six cycles in total) followed by D2 surgery and group B for D2 surgery (three cycles in total). The primary endpoint is the rate of pathological complete response and the secondary endpoints are R0 resection rate, three-year disease-free survival, five-year overall survival and safety.

This description comes directly from the study's public registry record.

Talk to the study team

Xinxin Wang, MD  ·  +8613811858199  ·  301wxx@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

Chinese PLA General HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04483076