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Study identifier: NCT04482374 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Puberty Suppression and Cardiometabolic Health

Condition: Transgenderism · Insulin Sensitivity/Resistance · Endothelial Dysfunction  ·  Sponsor: University of Colorado, Denver

PhaseN/A
Planned participants30
Who can joinMale, 9 Years to 14 Years
Healthy volunteersNo

About this study

This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin releasing hormone agonist compared to matched cisgender male controls.

This description comes directly from the study's public registry record.

Talk to the study team

Natalie J Nokoff, MD, MSCS  ·  720-777-6128  ·  natalie.nokoff@childrenscolorado.org

Always discuss trial participation with your own doctor first.

Locations (1)

University of Colorado Anschutz Medical CampusAurora, Colorado, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04482374