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Study identifier: NCT04468061 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

Condition: Breast Cancer · Triple Negative Breast Cancer · PD-L1 Negative  ·  Sponsor: Dana-Farber Cancer Institute

PhasePhase 2
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: * Sacituzumab govitecan (Trodelvy™;IMMU-132) * Pembrolizumab (Keytruda®; MK-3475)

This description comes directly from the study's public registry record.

Talk to the study team

Ana C Garrido-Castro, MD  ·  617-632-6409  ·  Ana_Garrido-Castro@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (15)

Stamford HospitalStamford, Connecticut, United StatesRecruiting
Miami Cancer Institute at Baptist Health (Kendall)Miami, Florida, United StatesRecruiting
Miami Cancer Institute at Baptist HealthPlantation, Florida, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Eastern Maine Medical CenterBrewer, Maine, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
DFCI @ FoxboroughFoxborough, Massachusetts, United StatesRecruiting
DFCI @ Milford Regional HospitalMilford, Massachusetts, United StatesRecruiting
DF/BWCC in Clinical Affiliation with South Shore HospitalSouth Weymouth, Massachusetts, United StatesRecruiting
The University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting
The Christ Hospital Cancer CenterCincinnati, Ohio, United StatesRecruiting
Ohio State University Medical CenterColumbus, Ohio, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04468061