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Study identifier: NCT04467502 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Virtual Reality Exposure Therapy for Gambling Disorder

Condition: Gambling Disorder  ·  Sponsor: University Hospital, Lille

PhaseNA
Planned participants124
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Gambling disorder (GD) is recognized as an addictive disorder in the DSM-5. Craving is a core phenomenon in addiction that can lead to relapse in problem gambling for pathological gamblers. Exposure Therapy (ET) focuses on craving in addiction treatment. ET in Cognitive-Behavioral Therapy (CBT) is based on classical conditioning that addresses the association between contextual cues and the craving response. ET helps the patient to reduce craving when faced with cues triggering craving. ET includes in vivo exposure and imaginal exposure. The literature recommends being as close as possible to the context of addiction to facilitate the extinction of craving but in vivo ET is complicated to perform. For GD, in outpatient consultation, bringing a patient to a casino presents obstacles (e.g., time, human and financial cost, agreement with casino for therapy). The study will be to assess the effectiveness of Virtual Reality Exposure Therapy (VRET) in a virtual gambling environment. Various trials show that VRET is no more or less effective than classical ET in CBT but has other advantages for motivation to treatment. This research aims to compare efficacy between CBT with VRET and CBT with imaginal exposure for treatment of GD in a multicenter, randomized, controlled, non-inferiority clinical trial.

This description comes directly from the study's public registry record.

Talk to the study team

Pierre TAQUET, PhD  ·  0320445838  ·  pierre.taquet@chru-lille.fr

Always discuss trial participation with your own doctor first.

Locations (10)

CHU Amiens-PicardieAmiens, FranceNot Yet Recruiting
CH Boulogne sur mer CSAPABoulogne-sur-Mer, FranceNot Yet Recruiting
CHU de CaenCaen, FranceNot Yet Recruiting
Hôpital Fontan, CHU lilleLille, FranceNot Yet Recruiting
Assoriation Cédragir Lomme CSAPALomme, FranceNot Yet Recruiting
CH de l'arrondissement de Montreuil / CSAPAMontreuil-sur-Mer, FranceNot Yet Recruiting
CHU RouenRouen, FranceNot Yet Recruiting
CH de Saint Amand les EauxSaint-Amand-les-Eaux, FranceNot Yet Recruiting
CH Seclin Carvin CSAPASeclin, FranceRecruiting
Association GREID ValenciennesCSAPAValenciennes, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04467502