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Study identifier: NCT04460872 Synced from ClinicalTrials.gov · July 28, 2026
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Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

Condition: Spinal Cord Injury · Spinal Cord Injuries · Trauma, Nervous System  ·  Sponsor: North Florida Foundation for Research and Education

PhasePhase 2
Planned participants21
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete or complete spinal cord injury. The investigators hypothesize that LT+TRT treatment will improve muscle size and bone mineral density in men with low T and ambulatory dysfunction after incomplete or complete SCI, along with muscle fundtion and walking recovery in men with T low and ambulatory dysfunction ater incomplete SCI.

This description comes directly from the study's public registry record.

Talk to the study team

Joshua F Yarrow, PhD  ·  (352) 548-6477  ·  joshua.yarrow@va.gov

Dana M Otzel, PhD  ·  (352) 548-6477  ·  dana.otzel@va.gov

Always discuss trial participation with your own doctor first.

Locations (2)

North Florida/South Georgia Veterans Health SystemGainesville, Florida, United StatesRecruiting
Brooks RehabilitationJacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04460872