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Study identifier: NCT04460573 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Smart Boot Use to Measure Offloading Adherence

Condition: Diabetic Foot Ulcer  ·  Sponsor: University of Southern California

PhasePhase 2
Planned participants210
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to help people with diabetes who develop neuropathic diabetic foot ulcers (DFUs). These ulcers, or sores, if left untreated can increase the chance of amputation. Part of the treatment is to have the person wear a diabetic shoe or boot to help their foot heal. Sometimes people don't wear the boot like they are told. The investigators want to compare three different kinds of diabetic boots to see if they can help make it easier for people to wear their boots as instructed. The investigators will look at three groups of participants: the first group will use removable offloading with reinforced education emphasizing continuous wear, including during rest and sleep, and not to remove it at any time. The second group will use removable offloading consistent with standard of care and receive education on recommended wear during walking or standing, with permission to remove the device during rest and sleep. The third group will use a smart removable offloading device that provides real-time adherence feedback via a smartwatch and smartphone, with additional personalized education informed by remotely monitored adherence data. The investigators will also be looking at how much physical activity, like walking, the participants do. And they will compare how well participants sleep and rate their quality of life in the three different boots. The investigators think that giving participants information about how much they are wearing their boot using read…

This description comes directly from the study's public registry record.

Talk to the study team

Fabiola Rodriguez, MD  ·  3235162332  ·  fabiola.rodriguez@med.usc.edu

Bijan Najafi, PHD  ·  5244677127  ·  bnajafi@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Rancho Los Amigos National Rehabilitation CenterDowney, California, United StatesRecruiting
Verdugo Hills Hospital of USCGlendale, California, United StatesRecruiting
Clemente Clinical ResearchLos Angeles, California, United StatesRecruiting
Keck Medical Center of USCLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04460573