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Study identifier: NCT04456816 Synced from ClinicalTrials.gov · July 29, 2026
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A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria

Condition: Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy · Severe Proteinuria Due to Idiopathic Membranous Nephropathy  ·  Sponsor: SynAct Pharma Aps

PhasePhase 2
Planned participants23
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This study is an exploratory, randomized, double-blind, multicenter, placebo-controlled study with repeated doses of AP1189. The study population will consist of patients with idiopathic membranous nephropathy (iMN) and severe proteinuria who are on ACE inhibitor or angiotensin II receptor blocker treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Irene Sandholdt  ·  +45 2015 7033  ·  isa@croxxmed.com

Birgitte Telmer, MD  ·  +45 2015 1221  ·  bte@croxxmed.com

Always discuss trial participation with your own doctor first.

Locations (1)

Aarhus UniversitetshospitalAarhus, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT04456816