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Study identifier: NCT04449523 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions

Condition: Silent Stroke · Silent Cerebral Infarct · Fibrillation  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhaseN/A
Planned participants150
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction (SBI). However, the role of AF in the formation of lesions (SBIs) is less well established than its role in AIS and needs clarification. The investigators hypothesize that continuous rhythm monitoring will yield a similar incidence of AF diagnosis in patients with SBI as compared to patients with cryptogenic AIS. The primary objective is to assess the cumulative incidence of AF diagnosis at 24 months in patients with SBI.

This description comes directly from the study's public registry record.

Talk to the study team

Laurent Roten, PD Dr. med.  ·  +41 31 632 52 63  ·  laurent.roten@insel.ch

Thomas Meinel, Dr. med.  ·  +41 76 49 28 545  ·  thomas.meinel@insel.ch

Always discuss trial participation with your own doctor first.

Locations (8)

Universitätsspital GrazGraz, AustriaRecruiting
Charite BerlinBerlin, GermanyNot Yet Recruiting
Centre hospitalier universitaire vaudois (CHUV)Lausanne, Canton of Vaud, SwitzerlandRecruiting
Kantonsspital AarauAarau, SwitzerlandActive Not Recruiting
University Hospital BaselBasel, SwitzerlandRecruiting
Inselspital BernBern, SwitzerlandRecruiting
Kantonsspital St.GallenSankt Gallen, SwitzerlandRecruiting
Universitätsspital ZurichZurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT04449523