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Study identifier: NCT04448184 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial)

Condition: Hematologic Neoplasms  ·  Sponsor: Ottawa Hospital Research Institute

PhasePhase 3
Planned participants662
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

It is hypothesized that a strategy using prophylactic oral and intravenous Tranexamic Acid (TXA) with therapeutic platelet transfusions (if required) is safe and more effective than prophylactic platelet transfusions in patients undergoing an autologous hematopoietic stem cell transplantation (ASCT).

This description comes directly from the study's public registry record.

Talk to the study team

Sohail Robert, RN  ·  613-737-8899  ·  sorobert@ohri.ca

Alan Tinmouth, MD  ·  613-737-8899  ·  atinmouth@ohri.ca

Always discuss trial participation with your own doctor first.

Locations (12)

Tom Baker Cancer CentreCalgary, Alberta, CanadaRecruiting
Cross Cancer InstituteEdmonton, Alberta, CanadaRecruiting
Eastern Regional Health AuthoritySt. John's, Newfoundland and Labrador, CanadaRecruiting
Memorial UniversitySt. John's, Newfoundland and Labrador, CanadaNot Yet Recruiting
Dalhousie UniversityHalifax, Nova Scotia, CanadaNot Yet Recruiting
Hamilton Health Sciences - Juravinski Hospital and Cancer CentreHamilton, Ontario, CanadaRecruiting
London Health Sciences CentreLondon, Ontario, CanadaRecruiting
The Ottawa HospitalOttawa, Ontario, CanadaRecruiting
Niagara Health SystemSt. Catharines, Ontario, CanadaRecruiting
Princess Margaret Cancer CentreToronto, Ontario, CanadaWithdrawn
Hopital Maisonneuve-RosemontMontreal, Quebec, CanadaNot Yet Recruiting
Saskatchewan Cancer AgencySaskatoon, Saskatchewan, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04448184