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Study identifier: NCT04448145 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Determinants of SARS (Severe Acute Respiratory Syndrome)-COV2 (COVID-19) Persistence After Convalescence

Condition: COVID-19 · Corona Virus Infection · SARS-CoV 2  ·  Sponsor: Columbia University

PhaseN/A
Planned participants800
Who can joinAll sexes, 7 Years to no upper limit
Healthy volunteersNo

About this study

The 2019-2020 COVID-19 pandemic is the largest outbreak in recent history. It is not known how long after someone gets sick with COVID-19 and recovers that they can still infect other people. It is also not known how quickly people make antibodies against the virus, which help clear infection from the body. The investigators will enroll 300 people who had COVID-19 based on lab testing or confirmed exposure to participate. An additional 25 participants who have never tested positive for COVID and have not had the vaccine will be enrolled as negative controls. Participants will complete a survey at enrollment. The investigators will also collect blood, nose swab, saliva, stool, semen, and breast milk to test for the virus. The investigators will ask participants to complete a survey and give specimens up to 12 times over 24 months. This information will be used to study how long the virus can live in different parts of the body, antibody development, and post-infectious complications. The investigators hope that this information will allow medical and public health providers to make recommendations to better care for patients in the convalescent phase of COVID-19 infection.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Yin, MD, MS  ·  212-305-7185  ·  mty4@cumc.columbia.edu

Lawrence Purpura, MD, MPH  ·  212-305-2220  ·  lp2745@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Medical CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04448145