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Study identifier: NCT04443088 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Condition: Cancer · Solid Tumor, Adult · Cancer Metastatic  ·  Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

PhasePhase 1
Planned participants78
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase 1, open-label dose-escalation study to determine the MTD of INV-1120 and RP2D, and to assess the DLT of INV-1120 as a single agent or in the combination with pembrolizumab. The safety, tolerability, and PK of INV-1120 as a single agent or in the combination with pembrolizumab will be assessed in adult patients with advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

radhika Shah, MD  ·  1 984 459 5523  ·  radhika.shah@syneoshealth.com

Always discuss trial participation with your own doctor first.

Locations (3)

Horizon Oncology Research, LLC,Lafayette, Indiana, United StatesCompleted
STARTSan Antonio, Texas, United StatesCompleted
UT HealthSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04443088