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Study identifier: NCT04442191 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Convalescent Plasma as a Possible Treatment for COVID-19

Condition: COVID-19  ·  Sponsor: University of Illinois at Chicago

PhasePhase 2
Planned participants50
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

Patients who are ill with COVID-19 may benefit from receiving convalescent plasma infusions containing antibodies from donors who have recovered from the disease and are proven to no longer be infected. Given the current public health emergency due to COVID-19, the FDA has recently fast-tracked the use of convalescent plasma. The purpose for this study is to assess if convalescent plasma collected from donors previously infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, can provide clinical benefit to those acutely ill with the virus and to evaluate if such treatment is safe. There will be two arms in the interventional study, where subjects will either be treated with convalescent plasma or fresh frozen plasma in a randomized and blinded manner. As an additional comparison, the clinical course of subjects enrolled during the period of the study who do not receive an alternative treatment for COVID-19 will be assessed.

This description comes directly from the study's public registry record.

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Locations (1)

University of Illinois at ChicagoChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04442191