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Study identifier: NCT04440280 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Condition: Fuchs Endothelial Corneal Dystrophy  ·  Sponsor: Massachusetts Eye and Ear Infirmary

PhasePhase 2
Planned participants45
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

This protocol will investigate whether topical application of N-acetyl cysteine (NAC) eye drops decreases oxidative stress and confers cytoprotection in patients with FECD.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Cheung, MSc, CCRP  ·  6175736060  ·  mcheung0@meei.harvard.edu

Ula Jurkunas, MD  ·  617-573-4330  ·  Ula_Jurkunas@meei.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts Eye and Ear InfirmaryBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04440280