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Study identifier: NCT04440267 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage

Condition: Acute Leukemia of Ambiguous Lineage  ·  Sponsor: Institute of Hematology & Blood Diseases Hospital, China

PhasePhase 2
Planned participants50
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

In this prospective, single arm, open label, clinical trial, a total of 50 acute leukemia of ambiguous lineage patients will be enrolled. Patients will receive acute lymphoblastic leukemia (ALL) -based chemotherapy and are permitted to receive allogeneic hematopoietic stem cell transplantation (HSCT) after CR . Otherwise, they will finish the consolidation chemotherapy. Patients with t(9;22) will receive chemotherapy combined with tyrosine kinase inhibitors. The purpose of current study is to evaluate the clinical efficacy of ALL-based chemotherapy,effect of genetic abnormality and minimal residual disease (MRD) on prognosis in patients with acute leukemia of ambiguous lineage.

This description comes directly from the study's public registry record.

Talk to the study team

Jianxiang Wang, Dr  ·  86-22-23909120  ·  wangjx@ihcams.ac.cn

Always discuss trial participation with your own doctor first.

Locations (1)

HBDHTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04440267