Condition: Extensive Stage Lung Small Cell Carcinoma · Sponsor: National Cancer Institute (NCI)
This phase II/III trial compares the effect of adding radiation therapy to the usual maintenance therapy with atezolizumab versus atezolizumab alone in patients who have already received atezolizumab plus chemotherapy for the treatment of small cell lung cancer that has spread outside of the lung or to other parts of the body (extensive stage). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving radiation therapy in addition to atezolizumab may extend the time without extensive small cell lung cancer growing or spreading compared to atezolizumab alone.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | Active Not Recruiting |
| Katmai Oncology Group | Anchorage, Alaska, United States | Recruiting |
| Cancer Center at Saint Joseph's | Phoenix, Arizona, United States | Recruiting |
| Mayo Clinic Hospital in Arizona | Phoenix, Arizona, United States | Suspended |
| Mayo Clinic in Arizona | Scottsdale, Arizona, United States | Suspended |
| Banner University Medical Center - Tucson | Tucson, Arizona, United States | Active Not Recruiting |
| University of Arizona Cancer Center-North Campus | Tucson, Arizona, United States | Active Not Recruiting |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro, Arkansas, United States | Recruiting |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Irvine, California, United States | Recruiting |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange, California, United States | Active Not Recruiting |
| Palo Alto Medical Foundation Health Care | Palo Alto, California, United States | Suspended |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville, California, United States | Suspended |
+ 404 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04402788