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Study identifier: NCT04378023 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Perihilar Cholangiocarcinoma. A Prospective Multicenter Study.

Condition: Unresectable Cholangiocarcinoma  ·  Sponsor: Hospital Vall d'Hebron

PhaseN/A
Planned participants34
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

A prospective multicentre study which includes patients ≤ 70 years-old diagnosed of unresectable perihilar cholangiocarcinoma (pCCA) ≤3cm in radial diameter, without evidence of lymph node or distant metastases. Liver transplantation preceded by neoadjuvant radiochemotherapy will be performed in this selected group. The primary endpoint will be overall survival at 1, 3, and 5 years post-transplant. The secondary endpoints will be: 1) recurrence-free survival at 1, 3 and 5 years post-transplant; 2) intention-to-treat survival of all patients included in the study at 1,3 and 5 years; 3) the rate of patients included in the study who are finally transplanted.

This description comes directly from the study's public registry record.

Talk to the study team

CRISTINA DOPAZO, MD/PhD  ·  +34932746113  ·  cristina.dopazo@vallhebron.cat

Always discuss trial participation with your own doctor first.

Locations (1)

Department of HPB Surgery and Transplants, Hospital Vall d´HebronBarcelona, Barcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT04378023