Condition: Breast Cancer · Sponsor: European Breast Cancer Research Association of Surgical Trialists
The optimal surgical axillary staging technique in patients who convert from the clinically positive to clinically negative lymph node status under neoadjuvant therapy (cN+ → ycN0) remains to be clarified. Different strategies (axillary lymph node dissection, sentinel node biopsy, targeted axillary dissection) are currently used in different countries. A prospective analysis comparing these techniques regarding feasibility, safety, morbidity and surgical effort is urgently needed. Due to high complexity and discordant recommendations, a randomized trial comparing different techniques is hardly feasible. Therefore, the EUBREAST study group decided to initiate a prospective cohort study as an international project that aims at comparatively evaluating data on axillary staging after neoadjuvant therapy.
This description comes directly from the study's public registry record.
Thorsten Kühn, Prof. · +49711 3103-3051 · info@eubreast.com
Maggie Banys-Paluchowski, PD Dr. · m.banys@outlook.com
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| Klinikum Esslingen | Esslingen am Neckar, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04373655