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Study identifier: NCT04373564 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

Condition: Motor Function · Cognitive Function · Contrast Media  ·  Sponsor: Guerbet

PhasePhase 4
Planned participants2076
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (GBCAs) have an effect on body movement and mental skills when given to participants multiple times within 5 years. The study plans to enroll about 2076 participants suffering from a condition for which they are likely to have at least annually a MRI or another imaging examinations. Only adults up to 65 years will be considered to join this study. During the study duration of 5 years participants will receive annually a MRI or other imaging tests (such as CT-scan, x-ray) and will visit the study doctor at least 7 times for physical examinations, laboratory investigations and tests on body movement and mental skills.

This description comes directly from the study's public registry record.

Talk to the study team

Nathalie LE FUR, PhD  ·  +33649351166  ·  nathalie.lefur@guerbet.com

Frantz HEBERT  ·  +33680249334  ·  frantz.hebert@guerbet.com

Always discuss trial participation with your own doctor first.

Locations (51)

Scottsdale Medical Imaging, LLCScottsdale, Arizona, United StatesRecruiting
Yale University School of MedicineNew Haven, Connecticut, United StatesWithdrawn
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Methodist Medical Center of IllinoisPeoria, Illinois, United StatesRecruiting
Massachussets General HospitalBoston, Massachusetts, United StatesRecruiting
Boston University Medical CenterBoston, Massachusetts, United StatesTerminated
Beth Israel Deaconess Medical CenterBoston, Massachusetts, United StatesWithdrawn
ActivMed Practices & Research, Inc.Methuen, Massachusetts, United StatesWithdrawn
University of Massachusetts Memorial Medical CenterWorcester, Massachusetts, United StatesTerminated
Department of RadiologySt Louis, Missouri, United StatesWithdrawn
UNC School of MedicineChapel Hill, North Carolina, United StatesWithdrawn
Penn State Hershey Medical CenterHershey, Pennsylvania, United StatesRecruiting

+ 39 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04373564