Condition: Acute GVHD · Sponsor: University of Kansas Medical Center
The purpose of this study is to determine whether the carbohydrate prebiotic (dietary supplement) known as galacto-oligosaccharide (GOS) can modulate the microbiome (the bacteria in the gut) and help prevent graft-versus host disease (GVHD) after allogeneic stem cell transplant. The study has two two parts. In phase 1, the best dose of GOS will be evaluated. In phase 2, using the best dose of GOS, participants will be randomized to receive GOS or a placebo (maltodextrin, a common food additive that is not known to affect the microbiome) so that the effect of GOS can be determined.
This description comes directly from the study's public registry record.
Beth Turk, MPH, CCRC · (913) 574-0154 · bturk2@kumc.edu
Always discuss trial participation with your own doctor first.
| Kansas University Medical Center | Kansas City, Kansas, United States | Recruiting |
| Duke | Durham, North Carolina, United States | Active Not Recruiting |
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Source record: clinicaltrials.gov/study/NCT04373057