Condition: Pancreatic Neoplasms · Sponsor: University Hospital, Montpellier
Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival \<20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common examination for all patients with suspicious pancreatic mass. A method was recently developed : it preserves the sanitary sample, named EXPEL, which allows standard pathology examination and OMICS analyzes from the "rinse" liquid. After EUS/FNA in clinical practice, the content of the needle is rinsed in CytoLyt® preservative solution. After cytofiltration, this liquid is systematically discarded. Based on the EXPEL concept, we hypothesise that this all-patients inclusive approach ("Modified EXPEL" procedure) combined with the methodology to access proteomic and metabolomics information in these original samples will allow us to identify a series of clinically useful marker signatures that will ultimately be measurable, non-invasively, in the patient blood.
This description comes directly from the study's public registry record.
Régis SOUCHE, MD · +33467337069 · fr-souche@chu-montpellier.fr
Eric ASSENAT, MDPhD · +33467330137 · e-assenat@chu-montpellier.fr
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| Uh Montpellier | Montpellier, Montpellier, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04370574