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Study identifier: NCT04356755 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.

Condition: Systemic Sclerosis  ·  Sponsor: University Hospital, Toulouse

PhasePhase 2
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Ischemic digital ulcers (DUs) are a frequent complication in systemic sclerosis with a major impact on hand function and quality of life. Digital injection of cultured adipose-derived stromal cell (AdMSC) constitutes a promising approach to treat scleroderma-induced refractory ischemic DUs where no alternative therapy is validated. The aim of this phase 2 study is to compare efficacy and safety of digital injection of AdMSC versus placebo for healing refractory active ischemic digital ulcers in patients with systemic sclerosis.

This description comes directly from the study's public registry record.

Talk to the study team

Grégory PUGNET, MD, PHD  ·  05 61 77 71 26  ·  pugnet.g@chu-toulouse.fr

Always discuss trial participation with your own doctor first.

Locations (7)

Grenoble HospitalGrenoble, FranceNot Yet Recruiting
Lille HopsitalLille, FranceNot Yet Recruiting
Marseille HospitalMarseille, FranceNot Yet Recruiting
Montpellier HospitalMontpellier, FranceNot Yet Recruiting
Nantes HospitalNantes, FranceNot Yet Recruiting
Poitiers HospitalPoitiers, FranceNot Yet Recruiting
CHU de Toulouse - Hôpital PURPAN-TSAToulouse, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04356755