Condition: HIV · Non-HIV · Vagus Nerve Dysfunction · Sponsor: Icahn School of Medicine at Mount Sinai
The study team's prior research has shown that dysfunction of a specific nerve, called the vagus nerve, is associated with small intestinal bacterial overgrowth (SIBO), and that SIBO is associated with signs of inflammation in the blood of people living with HIV (PLWH). This research will explore pathways linking vagal dysfunction to inflammation in HIV, focusing on the gastrointestinal tract, and study whether a medication called pyridostigmine and stimulation of the vagus nerve are beneficial therapies.
This description comes directly from the study's public registry record.
Niyati Neupane · niyati.neupane@mssm.edu
Mary Catherine George, MM, PhD · 212-241-0784 · mary-catherine.george@mssm.edu
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| Icahn School of Medicine at Mount Sinai | New York, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04353778