Condition: Obesity · Sponsor: University of North Carolina, Chapel Hill
The goal of this study is to understand the role of brain glucose transport in individuals with obesity and the association with cerebral hypometabolism and these individuals' response to plasma glucose elevations. The main premise is that obesity leads to reduced brain glucose transport and that we can measure this reduction with magnetic resonance spectroscopy (MRS). The secondary premises are that this reduction is driven by elevated non esterified fatty acids which act to turn on specific signaling pathways that regulate brain GLUT1 levels.
This description comes directly from the study's public registry record.
Joseph Palmiotto · 919-966-9184 · joseph_palmiotto@med.unc.edu
Always discuss trial participation with your own doctor first.
| Biomedical Research Imaging Center Marsico Hall (UNC) | Chapel Hill, North Carolina, United States | Recruiting |
| Clinical and Translational Research Center (CTRC) Burnett-Womack Building (UNC) | Chapel Hill, North Carolina, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04328337