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Study identifier: NCT04321512 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

Condition: Myocardial Infarction · Stroke, Ischemic · Ischemia  ·  Sponsor: UConn Health

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients. Ischemic Strokes (clots) occur as a result of an obstruction within a blood vessel supplying blood to the brain. A type of monocyte carrying a surface marker called "P2X4" helps the immune system sense and respond to danger signals from the body such as heart muscle and brain tissue injuries. The researchers expect to learn more about how these monocyte cells react to heart and brain tissue injury, and how the cells may then produce proteins or other chemical substances which promote the healing of heart muscle after heart attack and brain tissue after an ischemic stroke.

This description comes directly from the study's public registry record.

Talk to the study team

Fahad Shah, BSc.  ·  860-679-2692  ·  fshah@uchc.edu

Adrianna G. Perez  ·  adrperez@uchc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Connecticut Health CenterFarmington, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04321512