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Study identifier: NCT04319367 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs).

Condition: HIV/AIDS and Infections  ·  Sponsor: Imperial College London

PhasePhase 2
Planned participants72
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

RIO is a placebo-controlled double-blinded two arm prospective phase II randomised controlled trial . This study will test the use of broadly neutralising antibodies (bNAbs) in participants with treated primary HIV infection (PHI).

This description comes directly from the study's public registry record.

Talk to the study team

Stephen Fletcher  ·  +44 (0) 20 7594 7324  ·  rio_trial@imperial.ac.uk

Always discuss trial participation with your own doctor first.

Locations (12)

Aarhus University HospitalAarhus, DenmarkRecruiting
University Hospitals Sussex NHS Foundation TrustBrighton, United KingdomRecruiting
Western General HospitalEdinburgh, United KingdomRecruiting
Imperial College NHS Healthcare TrustLondon, United KingdomRecruiting
Barts Health NHS TrustLondon, United KingdomRecruiting
Chelsea And Westminster Hospital NHS Foundation TrustLondon, United KingdomRecruiting
Guy's and St Thomas' NHS Foundation TrustLondon, United KingdomRecruiting
Mortimer Market CNWL Hospital NHS Foundation TrustLondon, United KingdomRecruiting
Royal Free London NHS Foundation TrustLondon, United KingdomRecruiting
St Georges Hospital NHS Foundation TrustLondon, United KingdomRecruiting
Manchester University NHS Foundation TrustManchester, United KingdomRecruiting
Oxford University HospitalsOxford, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT04319367