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Study identifier: NCT04312451 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prospective Cohort of Patients With Critical Limb Ischemia Undergoing Revascularization

Condition: Critical Limb Ischemia  ·  Sponsor: Fondation Hôpital Saint-Joseph

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Peripheral Arterial Occlusive Disease is associated with a high risk of cardiovascular events. The critical ischemia stage represents the most severe stage of Peripheral Arterial Occlusive Disease, associated with decubitus pain and / or foot ulceration. The severity of this arterial involvement involves functional prognosis of the lower limb with a high risk of amputation, and the vital prognosis of the patient. In these patients, the rate of amputation and mortality at 1 year can reach 20%. Therefore, the goal of management in a multidisciplinary setting is limb salvage and improvement of the patient's vital prognosis. In the vascular medicine department, the indication and modalities of the revascularization procedure are discussed in a multidisciplinary consultation meeting. Surgical revascularization by distal bypass requires venous material that can be used, a receiving artery without diffuse lesions, in direct continuity with the arterial network of the foot, and the absence of co-morbidities against general anesthesia. With the modernization and development of endovascular equipment dedicated to the hamstrings, the interventional radiology techniques in the management of critical ischemia allow the treatment of one or more arterial axes as well as a very distal revascularization in the arteries. of the foot with less morbidity-mortality compared to surgery, especially in patients the most fragile patients. Since 2013, the endovascular revascularization procedures per…

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra YANNOUTSOS, MD  ·  144123568  ·  ayannoutsos@hpsj.fr

Helene BEAUSSIER, PharmD, pHD  ·  144127038  ·  crc@hpsj.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Groupe Hospitalier Paris Saint-JosephParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04312451