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Study identifier: NCT04312126 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Beneficial Effects of Naps on Motor Learning

Condition: Stroke  ·  Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

PhaseN/A
Planned participants199
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

Background: Memory consolidation is the process by which memories become stable, long-term representations in the brain. Consolidation of a motor skill is dependent upon sleep. Some research shows that daytime naps improve people s motor performance and memory retention. Researchers want to find out how daytime naps may contribute to learning and support consolidation of motor skill memories. Objective: To learn the role of memory replay during wakeful rest and sleep (naps) in retaining a newly learned skill. Eligibility: English-speaking adults ages 18 and older with chronic stroke, or healthy, right-handed, English-speaking adults ages 18-35 and 50-80 Design: Participants will be screened with: * medical history * neurological history * medicine review * medical exam * neurological exam. Participants will have a magnetic resonance imaging (MRI) scan of the brain. For this, they will lie down in a scanner. The scanner makes loud noises, so they will wear earplugs. They will fill out an MRI screening form before each MRI. Participants will also have magnetoencephalography (MEG). MEG maps brain activity. It does this by recording the magnetic fields produced by naturally occurring electrical currents in the brain. For MEG, participants will lie down in the MEG room. Their eye movements may be recorded by a video camera. Participants will have behavior testing. They will practice typing random keys. Then they will repeatedly type a custom sequence that they see on a …

This description comes directly from the study's public registry record.

Talk to the study team

Tasneem F Malik, C.R.N.P.  ·  (301) 496-4000  ·  tasneem.malik@nih.gov

Leonardo G Cohen, M.D.  ·  (301) 496-9782  ·  cohenl1@mail.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04312126