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Study identifier: NCT04310930 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Condition: Pulmonary Disease Due to Mycobacteria (Diagnosis)  ·  Sponsor: The University of Queensland

PhasePhase 2/Phase 3
Planned participants300
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Mycobacterium abscessus (MABS) is a group of rapid-growing, multi-drug resistant non-tuberculous mycobacteria (NTM) causing infections in humans. MABS pulmonary disease (MABS-PD) can result in significant morbidity, increased healthcare utilisation, accelerated lung function decline, impaired quality of life, more challenging lung transplantation, and increased mortality. While the overall numbers affected is small, the prevalence of infections is increasing worldwide. The Finding the Optimal Regimen for Mycobacterium abscessus Treatment (FORMaT) trial aims to produce high quality evidence for the best treatment regimens to maximise health outcomes and minimise toxicity and treatment burden, as well as developing biomarkers (serology, gene expression signatures, and radiology) to guide decisions for starting treatment and measuring disease severity in patients with MABS PD.

This description comes directly from the study's public registry record.

Talk to the study team

Claire Wainwright, MD  ·  +61730697322  ·  claire.wainwright@health.qld.gov.au

Kara Brady, MPharm  ·  +61730697618  ·  FORMaTtrial@health.qld.gov.au

Always discuss trial participation with your own doctor first.

Locations (50)

St George HospitalKogarah, New South Wales, AustraliaRecruiting
Queensland Children's HospitalSouth Brisbane, Queensland, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, Queensland, AustraliaRecruiting
Austin HospitalHeidelberg, Victoria, AustraliaRecruiting
Royal Melbourne HospitalParkville, Victoria, AustraliaRecruiting
Royal Perth HospitalPerth, Western Australia, AustraliaRecruiting
Royal Adelaide HospitalAdelaide, AustraliaRecruiting
Sunshine Coast University HospitalBirtinya, AustraliaRecruiting
Royal Prince Alfred HospitalCamperdown, AustraliaNot Yet Recruiting
The Prince Charles HospitalChermside, AustraliaRecruiting
Gold Coast University HospitalGold Coast, AustraliaRecruiting
Greenslopes Private Hospital,Greenslopes, AustraliaRecruiting

+ 38 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04310930