Condition: Postpartum Hemorrhage · Sponsor: University Hospital, Bordeaux
Several randomized, controlled trials, mostly involving women undergoing cesarean delivery, have shown that the prophylactic intravenous administration of 1 g of tranexamic acid after childbirth reduced blood loss. Most were small, single-centre trials with considerable methodologic limitations. It is important to emphasize that none of these RCTs has included women at increased risk of PPH such as placenta previa, a context in which the prevalence of moderate and severe blood loss is significantly higher and where the magnitude of the effect of TXA may highly differ compared to low risk women
This description comes directly from the study's public registry record.
Loic Sentilhes, MD, PhD · +335 56 79 55 79 · loic.sentilhes@chu-bordeaux.fr
Aurélie Darmaillacq · aurelie.darmaillacq@chu-bordeaux.fr
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| CHU Bordeaux | Bordeaux, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04304625