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Study identifier: NCT04298255 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples

Condition: Infertility, Male  ·  Sponsor: Wake Forest University Health Sciences

PhaseNA
Planned participants50
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is to evaluate if special types of cells called round spermatids can be gathered from men with non-obstructive azoospermia and used (in absence of elongated spermatids and spermatozoa) to reliably and effectively create pregnancy with a procedure called Round Spermatid Injection (ROSI). This process is similar to In Vitro Fertilization, or 'IVF'. In addition, this study wants to test the safety of ROSI and see what effects (good and bad) it has on embryo created from this method.

This description comes directly from the study's public registry record.

Talk to the study team

Karla M Oliver  ·  336-713-3123  ·  kaoliver@wakehealth.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Carolinas Fertility Institute (CFI)Winston-Salem, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04298255