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Study identifier: NCT04289571 Synced from ClinicalTrials.gov · July 28, 2026
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Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Condition: Cone-Rod Degeneration · Rod-Cone Degeneration  ·  Sponsor: National Eye Institute (NEI)

PhasePhase 1
Planned participants165
Who can joinAll sexes, 5 Years to 120 Years
Healthy volunteersYes

About this study

Background: The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier and more accurate way to assess mobility. Objective: To learn if researchers can track changes in mobility in people with retinal disease using a new VR tool. Eligibility: People aged 5 and older with retinal disease that affects their vision, and healthy volunteers. Design: Participants will have 2-3 clinic visits. Participants will wear goggles or sit in front of a screen while sitting. Using a game controller, they will navigate through 4 obstacle courses presented in VR. Participants will have a medical history exam. They will answer questions about their family history. They will fill out questionnaires about the vision and mobility issues they have in their daily lives. Participants will have a complete eye exam. They will read letters from a chart. Their eye pressure will be measured. Their pupils may be dilated with eye drops. Pictures of their eye will be taken. Lights will be shined in their eyes. Participants will take a visual field test. For this, they will look into a dome and press a button when they see a light. Participants will have an electroretinogram. For this, they will sit in the dark with their eyes patched. Then their eyes will be numbed with eye drops and t…

This description comes directly from the study's public registry record.

Talk to the study team

Daniel W Claus, R.N.  ·  (301) 451-1621  ·  daniel.claus@nih.gov

Brett G Jeffrey, Ph.D.  ·  (301) 402-2391  ·  jeffreybg@mail.nih.gov

Always discuss trial participation with your own doctor first.

Locations (2)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting
University of SydneySydney, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT04289571