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Study identifier: NCT04288999 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer

Condition: Rectal Cancer Recurrent  ·  Sponsor: National Cancer Center Hospital East

PhasePhase 3
Planned participants110
Who can joinAll sexes, 20 Years to 80 Years
Healthy volunteersNo

About this study

JCOG1801 is a randomized phase III trial which was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy for local relapse-free survival over standard treatment, i.e. surgery plus adjuvant chemotherapy, for previously non-irradiated locally recurrent rectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Yuichiro Tsukada, MD,PhD  ·  +80-4-7133-1111  ·  yutsukad@east.ncc.go.jp

Masaaki Ito, MD, PhD  ·  +80-4-7133-1111  ·  maito@east.ncc.go.jp

Always discuss trial participation with your own doctor first.

Locations (45)

Chiba Cancer CenterChiba, JapanRecruiting
Gifu University School of MedicineGifu, JapanRecruiting
Saitama Medical University International Medical CenterHidaka, JapanNot Yet Recruiting
Kansai Medical University HospitalHirakata, JapanNot Yet Recruiting
Hiroshima City Asa Citizens HospitalHiroshima, JapanRecruiting
Hiroshima City HospitalHiroshima, JapanRecruiting
Shimane University Faculty of MedicineIzumo, JapanRecruiting
Ishikawa Prefectural Central HospitalKanazawa, JapanRecruiting
National Cancer Center Hospital EastKashiwa, JapanRecruiting
Saitama Medical Center, Saitama Medical UniversityKawagoe, JapanRecruiting
Kochi Health Sciences CenterKochi, JapanRecruiting
Kumamoto University HospitalKumamoto, JapanRecruiting

+ 33 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04288999