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Study identifier: NCT04284969 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PROADAPT-ovary/EWOC-2

Condition: Ovarian Cancer · Surgery  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants292
Who can joinFemale, 70 Years to no upper limit
Healthy volunteersNo

About this study

PROADAPT is a standardized geriatric intervention that is currently being co-constructed during an exploratory phase on a multi-professional and multi-disciplinary basis after a systematic analysis of published data (Figure). It consists in: 1) before surgery: a prehabilitation of the patients including a nutritional, physical and educational preparation; 2) during the hospitalization for surgery: an optimisation of their treatments through a pharmaceutical conciliation, educational interventions, standardization of surgical procedures and enhanced rehabilitation after surgery; 3) bridging and post-discharge interventions for hospital-to-home transition. This intervention is based on a logic change model, constructed with literature data and validated by an expert group through a DELPHI method : the rehabilitation model. This intervention was designed to be implemented pragmatically in the centers according local habits and is currently being evaluated in several distinct hospital contexts under the name of "PROADAPT pilot study" in different tumor contexts thanks to a grant from the Regional Health Agency of Rhône-Alpes Auvergne region. PROADAPT intervention is planned to be evaluated in 4 tumor models inducing complex medico-surgical procedures considered at high risk of geriatric deconditioning. They have the same primary objectives in order to be evaluated into a meta-analysis. Results will be used to test the validity of the rehabilitation model. Therefore, it is a s…

This description comes directly from the study's public registry record.

Talk to the study team

Claire FALANDRY, PR  ·  4.78.86.32.87  ·  claire.falandry@chu-lyon.fr

Noual BAKRIN, MD  ·  naoual.bakrin@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (11)

Chu Bordeaux PellegrinBordeaux, FranceCompleted
CH Métropole SavoieChambéry, FranceRecruiting
Centre Georges François LeclercDijon, FranceRecruiting
Hôpital Croix RousseLyon, FranceRecruiting
Service de Gériatrie, Centre Hospitalier Lyon Sud, 165 chemin du Grand RevoyetPierre-Bénite, FranceRecruiting
Centre hospitalier Annecy GenevoisPringy, FranceRecruiting
CHU de St Etienne - Service gynécologieSaint-Priest-en-Jarez, FranceRecruiting
CHU Nord Saint Etienne - Service oncologie médicaleSaint-Priest-en-Jarez, FranceRecruiting
Institut Gustave RoussyVillejuif, FranceRecruiting
Médipôle Hôpital MutualisteVilleurbanne, FranceRecruiting
Villeurbanne Médipole MHPVilleurbanne, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04284969