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Study identifier: NCT04280822 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neo-adjuvant Immunochemotheray Versus Neo-adjuvant Chemotherapy for Resectable Esophageal Carcinoma

Condition: Esophageal Cancer · Surgery · Neoadjuvant Treatment  ·  Sponsor: Henan Cancer Hospital

PhasePhase 3
Planned participants400
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The effect of neo-adjuvant immunochemotherapy on survival of patients with thoracic esophageal squamous cell carcinomas remains unknown. One of our objectives is to evaluate whether the neo-adjuvant immunochemotherapy Toripalimab (JS001) with cisplatin and paclitaxel followed by right thoracic approach esophagectomy with total 2-field lymph node dissection improves the overall survival of thoracic esophageal cancer patients versus neo-adjuvant chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Yan Zheng, PhD, MD  ·  +86+15713660065  ·  sunnyzheng1@126.com

Haibo Sun, PhD, MD  ·  sunny-haipo@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Henan Cancer Hospital (The Affiliated Cancer Hospital of Zhengzhou University)Zhengzhou, Henan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04280822