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Study identifier: NCT04278404 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Condition: Coronavirus Infection (COVID-19) · Pulmonary Arterial Hypertension · Urinary Tract Infections in Children  ·  Sponsor: Duke University

PhaseN/A
Planned participants5000
Who can joinAll sexes, 0 Years to 20 Years
Healthy volunteersYes

About this study

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.

This description comes directly from the study's public registry record.

Talk to the study team

Chi Hornik  ·  (919) 260-7626  ·  chi.hornik@duke.edu

Melissa James, MPH, RD  ·  (704) 502-6491  ·  melissa.james@duke.edu

Always discuss trial participation with your own doctor first.

Locations (51)

Phoenix Children's HospitalPhoenix, Arizona, United StatesCompleted
Arkansas Children's Hospital Research InstituteLittle Rock, Arkansas, United StatesRecruiting
University of California, Los Angeles Medical CenterLos Angeles, California, United StatesRecruiting
Lucile Packard Children's HospitalPalo Alto, California, United StatesRecruiting
Colorado University DenverAurora, Colorado, United StatesRecruiting
The Children's Hospital ColoradoAurora, Colorado, United StatesCompleted
Alfred I. DuPont Hospital for ChildrenWilmington, Delaware, United StatesCompleted
University of Florida Jacksonville Shands Medical CenterJacksonville, Florida, United StatesRecruiting
Kapiolani Womens and Childrens Medical CenterHonolulu, Hawaii, United StatesRecruiting
Ann and Robert H. Lurie Childrens Hospital of ChicagoChicago, Illinois, United StatesCompleted
Ann and Robert H. Lurie Childrens Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Riley Hospital for Children at Indiana UniversityIndianapolis, Indiana, United StatesRecruiting

+ 39 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04278404