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Study identifier: NCT04273607 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Anticoagulation-free VV ECMO for Acute Respiratory Failure

Condition: Extracorporeal Membrane Oxygenation Complication  ·  Sponsor: Damian Ratano

PhasePhase 2/Phase 3
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Currently international experts recommend therapeutic anticoagulation for veno-venous extracorporeal membrane oxygenation (VV-ECMO). Reports and case series suggest that the absence of therapeutic anticoagulation is safe for VV-ECMO. No randomized control trials have assessed this. The aim of this pilot study is to assess safety and feasibility of an "anticoagulation-free strategy" for veno-venous ECMO (VV-ECMO) in Acute respiratory distress syndrome (ARDS).

This description comes directly from the study's public registry record.

Talk to the study team

Damian Ratano, MD  ·  +1 416-340-3601  ·  damian.ratano@chuv.ch

Eddy Fan, MD, PhD  ·  +1 416-340-3601  ·  eddy.fan@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Toronto General HospitalToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04273607