Condition: Infection · Pneumonia · Surgical Site Infection · Sponsor: University of Birmingham
PENGUIN is a pragmatic multi-center trial investigating the effects of pre-operative mouthwash and perioperative oxygen on the incidences of pneumonia and surgical site infection (SSI) following major abdominal surgery. Patients will be recruited from low and middle income countries and randomly assigned to a trial treatment arms: a) pre-operative chlorhexidine mouthwash and 80-100% FiO2; b) no pre-operative mouthwash and 80-100% fraction of inspired oxygen (FiO2); c) pre-operative chlorhexidine mouthwash and 21- 30% FiO2; or d) no pre-operative mouthwash and 21-30% FiO2.
This description comes directly from the study's public registry record.
Divya Kapoor · 01214159127 · penguin@trials.bham.ac.uk
Rachel Lillywhite, BA · 01214159127 · penguin@trials.bham.ac.uk
Always discuss trial participation with your own doctor first.
| Hospital das Clinicas da Faculdade de Medicina de Botucatu - UNESP | Botucatu, São Paulo, Brazil | Recruiting |
| Hospital de Clinicas de Porto Alegre | Porto Alegre, Brazil | Recruiting |
| Hospital Nossa Senhora da Conceicao | Porto Alegre, Brazil | Recruiting |
| Hospital Universitario Professor Edgar Santos/Bahia | Salvador, Brazil | Recruiting |
| Hospital Sao Jose - Criciuma/SC | São José, Brazil | Recruiting |
| Homi Bhabha Cancer Hospital & Research Centre | Visakhapatnam, Andhra Pradesh, India | Recruiting |
| Sher - i - Kashmir Institute of Medical Sciences | Srinagar, Jammu and Kashmir, India | Recruiting |
| Chinchpada Christian Hospital | Chinchpāda, Maharashtra, India | Recruiting |
| Kasturba Medical College Hospital, Manipal | Madhava Nagar, Manipal, Karnataka, India | Recruiting |
| Government Medical College, Patiala | Patiāla, Punjab, India | Recruiting |
| All India Institute of Medical Sciences, Bhubaneswar | Bhubaneswar, India | Recruiting |
| Government Medial College & Hospital, Chandigarh | Chandigarh, India | Recruiting |
+ 25 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04256798